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Advantages of KinExA

Advantages of a Kinetic Exclusion Assay (KinExA)

  • Can measure cellularly expressed proteins.
  • Measurements can be made with unpurified materials.
    (e.g. serum, cell lysates, ascites fluid, supernatants, etc.)
  • Measures a wide range of binding constants.
  • Versatile assay formats.
  • Can identify non-standard binding interactions such as cooperativity and mixtures.
  • No risk of mass transport limitations or artifacts that may mask true binding constants.
  • Highly reproducible.