Measuring Affinity & Kinetics: The essential guide to understanding KinExA technology & high-affinity binding

Agenda

Thursday, September 21st
Day One
Breakfast Provided @ Hotels or Continental Breakfast @ BSU Upon Arrival

​TownPlace Suites by Marriot Boise Downtown/University
Shuttle to Boise State University leaves @ 7:15 am
​Residence Inn Boise Downtown/University
Shuttle to BSU leaves @ 7:25 am
8:00 am
Welcome Address
Track 1
8:30 am
Introduction to KinExA Technology
Molly Dovner, Staff Scientist
Sapidyne Instruments
Boise, Idaho
What does KinExA stand for & how is it different than SPR? Learn how KinExA is commonly used & why it is important​
Track 2
​8:30 am
"​Making it Happen"
Elizabeth Hopkins, President & CEO
Sapidyne Instruments
Boise, Idaho
 Liz will highlight & discuss a few examples where KinExA user's have expanded the boundaries of what KinExA can measure &/or how KinExA measurements can be applied.  In some instances Sapidyne personnel have been actively involved while in others we learned about the innovation through peer reviewed literature.  We remain keenly interested in KinExA  users measurement problems, your questions, ideas, wishes, & even dreams will be welcomed.
9:45 am | Networking Break
Track 1
​10:15 am
Experimental Design | Assay Setup
Design an assay for a soluble system & prepare for an  Equilibrium Experiment
Track 2
​10:15 am
Advanced KinExA Theory Models
Learn about the advanced theory models within the KinExA Pro software & how to apply them to your research​

​
​11:30 am | Speaker
​​"SPR Surface Matrix Effects on the Binding Kinetics of an Antigen/Antibody Complex"
Andrew Drake, Sr. Principal Scientist, Discovery Biologics Research
Bristol Meyers Squibb
​Redwood City, California
12:15 pm | Catered Lunch
Track 1
​1:15 pm
Hands-On Training | Affinity Experiment Prep
Setup an equilibrium experiment with a soluble system on a KinExA 4000 instrument
Track 2
​1:15 pm
​​Experimental Design | Cell Assay Setup
Design an assay for a cell system & prepare for an  Equilibrium Experiment
​
​2:45 pm | Speaker
​​"Determine Binding Affinity of Therapeutic Antibodies to Integral Membrane Protein Targets"
Ching Chen, Scientist
​Amgen
​Thousand Oaks, California
Track 1
​3:15 pm
Introduction to the Theory Curve
Understand how the three basic models of the KinExA Theory Curve are used & how they help you understand binding interactions 
Track 2
​3:15 pm
Hands-On Training | Cell Affinity Experiment Prep
Setup an equilibrium experiment with a cell system on a KinExA 4000 instrument​
4:30 pm | Networking Break
4:45 pm | Speaker
​​"Examples of Positive Cooperativity in the Binding of Both Antibodies & their Protein Antigens"
Robert Blake, Professor
Xavier University
​New Orleans, Louisiana
5:15 pm
​Closing Remarks
​Shuttle Returns to Hotel
7:00 pm
Dinner Reception
Location TBD