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Trusted Accuracy, Proven Reliability, & Unrivaled Sensitivity
" By tailoring the KinExA to each studied antigen, we obtained apparent equilibrium dissociation constants (K(D) values) spanning six orders of magnitude, from approximately 100 fM to 100 nM. "
Bee C. et. al. 2012 Exploring the dynamic range of the kinetic exclusion assay in characterizing antigen-antibody interactions.
PLOS ONE 7(4) http://www.ncbi.nlm.nih.gov/pubmed/22558410
" The kinetics of binding and affinity of the 4 chimeric clones to human IL-21 were determined using a kinetic exclusion assay (KinExA)...Among the four lead clones, 19E3 had the highest affinity to recombinant human IL-21 of 243 fM "
Reena Varkey et. al. 2019 Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy. PLOS ONE