Sapidyne Newsletters

• Concentration measurements
• Anti-his Secondary antibody
• Online KinExA manual
• GREENics Korea
• How is cell expression level determined with KinExA and how does it compare to soluble titrant activity?
• 4000 signal output
• Coating PMMA with biotin

• Spotlight: Investigations of Influence of Antibody Binding Kinetics on Tumor Distribution and Anti-Tumor Efficacy
• Streptavidin coated beads
• Linear range
• Touring Idaho: Hiawatha bike trail
• Meet Sophie

• Spotlight: AlphaBind, a Domain-Specific Model to Predict & Optimize Antibody-Antigen Binding Affinity
• The future of solid phase; solid phase selection guide
• Time to upgrade to 4000
• Touring Idaho: Shoshone falls
• Meet Scooby

• Dr. Palaniswami Rathanaswami
• Implementing cleaning cycle
• Idaho news spotlight: Craters of the Moon monument
• Meet Birdy

• Spotlight: Unleashing Natural IL18 Activity Using an Anti-IL18BP Blocker Induces Potent Immune Stimulation and Antitumor Effects
• Q & A about bubbles, why need a high and low curve, can we measure affinity of soluble molecule to surface proteins of intact cell?
• Reducing NSB
• Meet Buddy
• Idaho news: Micron touts progress on large expansion to federal leaders

• Sapidyne mission statement
• Spotlight: high affinity antibodies using KinExA and SPR
• Tom’s long video
• KinExA mode test
• Preparing the experiment
• Olive oil taste test
• Idaho news spotlight: nuclear cleanup milestones and research advance

• KinExA seminar
• KinExA training
• Game night

• Temperature measurements and TC1000
• Tube Rotator
• Syringe purge
• Spotlight: Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence–based affinity maturation
• Why do measurements need to be performed with signals in the linear range?
• Autosampler calibration wizard
• Trade-up program
• Contract research

• Cell pellets
• Advanced flow cells for sticky systems
• Lamp replacement on 3200
• What is the difference between avidity and cooperativity?
• 21 CFR Part 11 compliance
• Employee spotlight: Frank
• Cleaner water with KinExA
• Article about measuring PAH availability in petroleum-impacted sediment
• Contract research

• Temperature effects on Kd
• TC1000
• Contract research
• Spotlight: capture surface and SPR
• What are the differences between KinExA and SPR?
• Software shortcuts
• Aluminum tape
• 25th Sapidyne anniversary

• Concentration measurements
• Anti-his Secondary antibody
• Online KinExA manual
• GREENics Korea
• How is cell expression level determined with KinExA and how does it compare to soluble titrant activity?
• 4000 signal output
• Coating PMMA with biotin

• Whole cell, cooperativity analysis, direct off rate, competitive binding
• Bead coating tips
• Spotlight: measuring affinity for a combination of 3 antibodies
• Is dielectric grease important for flow cell?
• Temperature tracking

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